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Table 1 Homologous regions between NDV viral proteins and human cellular proteins.

From: The matrix (M) protein of newcastle disease virus binds to human bax through its BH3 domain

Names

Sequences

Identity %

Score (Bits)

Gap %

AF2240-M

B-cell transcription factor 4 leukemia

27 LQDTGDGKKQI 38 LQDTGDILQQI

****** **

72.7

36.0

0.0

AF2240-M

Glucagon-like 1 receptor

297 QWDSLLSYSKCLS

213 QWDGLLSYQDSLS

*** **** **

69.0

27.8

0.0

AF2240-M

Cholecystokinin B receptor

128 VFSVVQA--PRVLQ

191 VYTVVQPVGPRVLQ

* *** *****

64.0

26.9

14.0

AF2240-M

Fibrous sheath-interacting 2

150 SVNAVNHVK

1506 SVNGGNHIK

*** ** *

66.0

20.2

0.0

AF2240-M

Spectrin beta chain, brain 4

46 LDSWTDS

2484 LDSWTDS

*******

100.0

26.5

0.0

AF2240-M

Cytochrome Oxidase

182 WDSLASFRKSLSP

298 WDSLLSYSKCLSP

**** * * ***

69.2

49.0

0.0

AF2240-M

RAS p21 protein activator

4 VLQDTGDGK

449 VLNDTVDGK

** ** ***

77.0

21.0

0.0

AF2240-M

Bid

80 DNPGHEL 95 DALGHEL

* ****

71.4

24.0

0.0

AF2240-M

Bax

298 WDSLLSY

158 WDGLLSY

** ****

85.7

46.0

0.0

AF2240-L

Bcl-2

1540 DFIEMSAKL

110 DFAEMSSQL

** *** *

66.7

31.0

0.0

AF2240-L

Bid

19 NTSRSEE

147 NVSRSEE

* *****

85.7

29.0

0.0

AF2240-L

Bid

86 LRTYVR 2145 LRTYLR

**** *

83.3

27.0

0.0

AF2240-L

Bad

451 EFEPCIEYD

6 EFEPSEQED

**** *

55.6

25.0

0.0

AF2240-F

F-box protein FBW7

21 LILSCICL

8 LILSCICL

********

100.0

29.9

0.0

  1. AF2240-M showed most matching sequences both to cellular proteins and also Bcl-2 family members compared to other viral proteins and strains.