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Table 3 Pigs immunized with rE2-a, rE2-b and rE2-ba elicited serum neutralizing antibodies early after viral challenge.

From: Multiple linear B-cell epitopes of classical swine fever virus glycoprotein E2 expressed in E.coli as multiple epitope vaccine induces a protective immune response

Groups Pigs Inoculum Neutralizing antibody titer
    day p.i. day p.c.
    0a 7 14b 21 28 35c 42(7) 49(14) 56(21) 63(28)
A 5 rE2-a < 2 < 2 4 16 32 32 64 64 64 64
B 5 rE2-b < 2 < 2 8 32 64 64 128 128 128 128
C 5 rE2-ba < 2 < 2 8 32 64 64 256 256 256 256
D 5 HCLV < 2 < 2 8 16 32 64 128 128 128 128
E 5 PBS < 2 < 2 < 2 < 2 < 2 < 2 < 2 < 2 < 2 0d
  1. Antibody titers were determined using a NPLA assay, as described in the study. Samples were collected every 7 days. a, first innoculation; b, second innoculation; c, CSFV strain Shimen challenge timepoint. d, all of the pigs in the group E had died after 28 dpc.