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Figure 4 | Virology Journal

Figure 4

From: Multiple linear B-cell epitopes of classical swine fever virus glycoprotein E2 expressed in E.coli as multiple epitope vaccine induces a protective immune response

Figure 4

Body temperature change (average body temperature curves of each group) of pigs after post-challenge of CSFV Shimen strain. Body temperature was measured every day. Symbol () represents the average body temperature of Group A (immunized with rE2-a). Symbol (■) represents the average body temperature of Group B (immunized with rE2-b). Symbol (▲) represents the average body temperature of Group C (immunized with rE2-ba). Symbol (×) represents the average body temperature of Group D (immunized with HCLV). Symbol (*) represents the average body temperature of Group E (immunized with PBS). Obviously, the average body temperature of Groups A, B and C waves in the normal body temperature range (39.0 ± 0.5°C) after post-challenge (dpi with CSFV Shimen strain). In contrast, the average body temperature of Group E in the same period is 1~2°C higher. All pigs immunized with PBS died during the period from 14 to 21 dpi.

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