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Table 1 Synthetic peptides of NS3358-375 and its variants

From: Characterization of antigenic variants of hepatitis C virus in immune evasion

Peptide name

Amino acid sequence

Time of isolation*

Wild type

NS3358-375

VIKGGRHLIFCHSKKKCD

 

VP1**

I366T F367L

--------TL--------

1.0

 

C368R

----------R-------

1.0

 

H369R

-----------R------

1.0

 

S370P

------------P-----

1.0, 2.4

 

K371E

-------------E----

1.0

 

C374R

----------------R-

2.4

VP2

V358G

G-----------------

1.0

 

V358A I366V

A-------V---------

1.0

 

I366V

--------V---------

2.4

 

C374S

----------------S-

2.4

  1. *: years after infection. **: VP means variant pool.
  2. Note: the core region of NS3358-37 encompasses amino acids 364-373.