Figure 4
Absence of RSV-induced inflammatory responses in lung and BAL following immunization with AdF.RGD. BALB/c mice were immunized subcutaneously with AdNull, AdF.RGD (both at 1010 pu), formalin-inactivated RSV (FIRSV, 105 pfu) or intranasally with RSV (106 pfu). Five wk later the mice were challenged intranasally with RSV (106 pfu) and lungs were harvested after 6 days. A-D. Cytokine levels in homogenates: A. Eotaxine levels in lung homogenate. B. IL-4 levels in lung homogenate. C. IL-13 levels in lung homogenate. D. IL-10 levels in lung homogenate Data are shown as mean ± SEM of duplicate measurements of n = 4 mice/group and represent one of two independent experiments.*** and * denote significance of p < 0.001 and p < 0.05, respectively.