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Table 1 Comparison of the genome length (nucleotides) of the fourteen HRSVA clinical strains and transition bias (R) in clinical strains with reference to strain RSV-1 (Clinical reference strain)

From: Whole genome characterization of non-tissue culture adapted HRSV strains in severely infected children

RSV A

Genome Length

% Nucleotide Variability

Transition Bias (R)

RSV -11

15,212

----

Ref strain (RSV-1)

RSV-2

15,210

1.42

2.4

RSV-3

15,218

2.36

2.3

RSV-4

15,219

2.14

2.4

RSV-5

15,214

0.6

2.1

RSV-6

15,220

1.72

1.2

RSV-7

15,222

1.42

1.4

RSV-8

15,212

1.95

1.9

RSV-9

15,219

1.15

1.8

RSV-10

15,218

2.38

2.2

RSV-11

15,215

3.3

2.1

RSV-12

15,211

3.1

2.8

RSV-13

15,215

2.9

2.7

RSV-14

15,218

1.88

1.9

Lab adapted reference strain

RSV A2

15222

3.30

2.9

RSS

15191

2.67

2.4

Long

15226

3.56

2.9

Line 19*

15191

3.58

2.9

  1. 1RSVA2 (lab adapted strain) is passaged several times in cell culture, thus may have numerous culture mediated mutations. Therefore, RSV-1, a strain obtained from a hospitalized RSVA patient is used as a reference strain for comparative analysis of RSVA strains from clinical source and published reference strains. * Nucleotide sequence for 5' and 3' ends of Line 19 is not available.
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Virology Journal

ISSN: 1743-422X