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Table 4 Distribution of each variable according to fibrosis stages (n = 157)

From: Association of laboratory parameters with viral factors in patients with hepatitis C

Factor

No/minimal fibrosis (F0/F1)

Significant fibrosis (F2/F3)

Cirrhosis (F4)

P value

Age

32.7 ± 9.4

40.3 ± 8.4

48.4 ± 7.1

0.000

Sex (M/F)

54/14

46/22

14/7

0.247

Genotype (1a/3a)

12/56

6/62

4/17

0.258

Viral load (IU/mL)

7.8 х 106±1.3 х 107

1.2 х 108±1.9 х 108

2.9 х 105±2.9 х 105

0.000

Hb level (mg/dl)

12.6 ± 1.2

12.8 ± 1.5

12.3 ± 1.2

0.328

Bilirubin (mg/dl)

0.83 ± 0.18

1.06 ± 0.31

1.62 ± 0.31

0.000

ALT (IU/mL)

118 ± 62.4

145.8 ± 76.2

147.5 ± 61.2

0.091

ALP (IU/mL)

81.5 ± 38.1

159.7 ± 79.2

323.8 ± 80.1

0.000

AST (IU/mL)

96.8 ± 63.7

101.5 ± 58.6

155.5 ± 90.6

0.004

AAR

1.03 ± 1.07

0.97 ± 1.06

1.26 ± 0.95

0.522