Dose response and cytotoxicity test. 1G5 cells were infected with NL4-3 and treated with increasing amount of HPBP 24 h post transfection. Luciferase activity was assessed 48 h post transfection. MTT test were performed in the same conditions than the dose response experiment. HIV-1 inhibition (grey columns) and percentage of living cell (green line) are shown relative to the mock treated conditions as 100%. Values correspond to an average of at least three independent experiments performed in duplicate.