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Figure 7 | Virology Journal

Figure 7

From: Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice

Figure 7

CCR5 upregulation is seen on CD8 cells in both WT and V38E mutant infected mice. Mice sacrificed at 8 weeks were assayed for CCR5 expression in both peripheral blood and spleen. Representative histograms of CCR5 expression in CD8 or CD4 cells in PBMCs (A) or Spleen (B) is shown for both WT and V38E Mutant. (C) Cumulative data from 3 mice on the expression of CCR5 on CD4 or CD8 cells at 8 weeks post infection in PBMCs or spleen cells is shown.

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