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Figure 6 | Virology Journal

Figure 6

From: Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice

Figure 6

CD4 decline correlates with CD8 immune activation in WT mice but not V38E mutant. Correlation of HLADR or PD-1 expression on CD8 cells with CD4 decline in WT and V38E infected groups was determined using Pearson's correlation coefficient. Correlation between HLADR expression on CD8 cells and CD4 decline for WT (A) and V38E (B) is shown. Similarly the correlation between PD-1 expression on CD8 cells and CD4 decline in WT (C) and V38E (D) was also determined.

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