Figure 3

NS5A does not co-localize with apoB crescents in sg-1b replicon cells treated with NIM811. Sg-1b replicon cells were treated and stained as in Figure 2. A) NS5A (red) localizes to regions that also contain apoB within replicon cells treated with DMSO, whereas NS5A and apoB no longer co-localize in the presence of NIM811. B) NS5A and lipid droplets are in close apposition, but the two do not co-localize in sg-1b replicon cells regardless of compound treatment.