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Table 1 Experiment design

From: Evaluation of several adjuvants in avian influenza vaccine to chickens and ducks

Parts

Birds

group

Boosting date a

Bleeding date

Challenging date b

Collection of swab c

  

Mineral oil

    
  

70M

    
  

70M

    

Part I

SPF chickens

206

 

2, 3, 4, 6, 8, and 13 w after primary immunization

13 w after primary immunization

 
  

rH5N3 Antigen

    
  

PBS

    
  

70 M

    
  

206

    

Part II

SPF ducks

rH5N3 Antigen

3 w p.v.d

0 day before initial immunization, 2, 6, and 9 w after primary immunization

  
  

PBS

    
  

70 M

    

Part III

SPF chickens

70 Mi(i = 1-8)

3 w p.v.

2, 3, 4, 6, 8, and 13 w after primary immunization

13 w after primary immunization

3, 7, and 10 days p.c.e

  

PBS

    
  1. aGroup I didn't perform boosting immunization
  2. bGroup II didn't conduct challenge experiments.
  3. cGroup I didn't collected trachea and cloaca swabs after challenge.
  4. dp.v.= post-vaccination
  5. ep.c.= post-challenge