Figure 1

Histopathologic changes of heart tissue in VMC mice. A. Representative image of inflammation in VMC heart tissue (H&E, original magnification × 400). B The pathological scores at different times, *P < 0.05, versus control group, ^ΔP < 0.05, versus week 0, 1, 3, 4, and 6 VMC mice, ^※P < 0.05, versus week 4 and 6 VMC mice. The number of mice in each time point of VMC group was 8, 8, 5, 6, 6 and 5 respectively. The number of mice in each time points of control was 5.