Graphical representation of combine effect of siRNA against HCV E2 gene and HCV receptors gene CD-81, LDLR on viral titer in serum infected Huh-7 cells. For Viral titer in Huh-7 cells treated with scrambled siRNAs (Sc) and CD-81 siRNA (siCD81-B), LDL siRNA (siLDLR), E2 siRNA (E2si873) either alone or in combinations and incubated for 6 hrs before adding HCV-3a sera (Ser 3a). HCV RNA levels were quantified by Real Time PCR. Three independent experiments with triplicate determinations were performed. Error bars indicate, mean S.D *p < 0.01 verses Ser3a.