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Figure 9 | Virology Journal

Figure 9

From: A novel fusogenic herpes simplex virus for oncolytic virotherapy of squamous cell carcinoma

Figure 9

Histopathological changes and virus gene expression in oral SCC xenografts in nude mice. Oral SCC xenografts in nude mice were given 1 × 106 PFUs of HF or RH2. After 3, 5, 7, and 14 days, they were subjected to immunohistochemical staining and the mean size (μm2) of HSV-1 antigen-positive multinucleated cells in the sections was determined. Data are means ± SD of three determinations. At 14 days, a significantly difference was observed between HF and RH2 (*P < 0.05).

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