Figure 8From: A novel fusogenic herpes simplex virus for oncolytic virotherapy of squamous cell carcinomaHistopathological changes and virus gene expression in oral SCC xenografts in nude mice. Oral SCC xenografts in nude mice were given 1 × 106 PFUs of R849 (a, b), HF (c, d), or RH2 (e, f). Tumors with skin were removed 7 days after infection and processed as described in Figure 7. Arrows indicate rounded cells (b) and multinucleated cells (d, f).Back to article page