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Table 1 amino acids substitution in HVR1 of E2 protein (Rapid responder group)

From: Characterization of Hepatitis C Virus genotype 3a Hypervariable region 1 in patients achieved rapid virological response to alpha interferon and Ribavirin Combination therapy

H

T

Y

T

T

G

G

T

A

A

R

N

T

K

G

L

A

G

L

F

Y

P

G

A

K

Q

K

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

26

27

N5

 

Y8

T5

T10

 

G10

S7

V5

 

S5

S7

 

S10

G10

 

T7

  

F14

S10

R5

  

S10

 

N10

V4

 

H7

V5

V4

 

S5

K5

I5

 

R5

T5

 

R5

S5

 

V5

  

L1

T4

S5

  

K5

 

K3

Q2

  

I3

A1

  

N3

A5

 

H3

N2

    

A3

   

D1

P5

    

R1

H2

  

P1

      

Y2

               

W1

K1

  

L1

                       
  1. Amino acid substitution at each amino acid position analyzed from pre-treatment patient samples that belong to rapid responder group (R.R). R.R group (3 samples and 15 clones) contains 10 conserved sites and 17 variable sites