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Table 1 HA-specific antibody titers measured by ELISA (Total IgG) or HAI in pooled sera and BAL of immunized mice

From: Intramuscular immunization of mice with live influenza virus is more immunogenic and offers greater protection than immunization with inactivated virus

   

IM vaccine type

IN infection

Test

Sample

Day post vaccination

Inactivated

Live

Live

ELISA (Total IgG)

Serum

0

<25

<25

<25

  

7

<25

<25

<25

  

28

400

800

100

  

7 days post-boost

800

1600

400

  

28 days post-boost

800

1600

800

 

BAL

0

<2

<2

<2

  

7

<2

<2

<2

  

28

16

64

32

  

7 days post-boost

32

64

64

  

28 days post-boost

16

64

64

HAI

Serum

0

<4

<4

<4

  

7

16

16

<4

  

28

64

256

256

  

7 days post-boost

128

256

128

  

28 days post-boost

128

512

128