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Figure 3 | Virology Journal

Figure 3

From: Intramuscular immunization of mice with live influenza virus is more immunogenic and offers greater protection than immunization with inactivated virus

Figure 3

Kinetics of cytokines present in (A) serum and (B) BAL following secondary IM immunization with live or inactivated A/WI/05, or after a secondary dose of live virus delivered IN. The concentration of cytokine was measured in samples collected from individual mice using multiplex MSD analysis. Mean values of IFN-γ, IL-4 and IL-5 in sera and BAL of 3 mice per group are shown for each time point following the boosting dose.

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