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Table 1 Allelic and genotypic frequencies of PrP in Damani and Hashtnagri, and Kamori and Local Hairy

From: Detection of Four Novel Polymorphisms in PrP gene of Pakistani sheep (Damani and Hashtnagri) and goats (Kamori and Local Hairy) breeds

 

Allelic frequencies

       
  

Sheep breeds

  

Goat breeds

 
  

Damani Hashtnagri

Both

 

Kamori

Local Hairy

Both

  

n/56

n/56

n/112

 

n/56

n/56

n/112

1

G127R151Y152Q171Q189T191

0.464

0.536

0.500

G22P63H143S240

0.232

0.375

0.304

2

SRYQQT

0.054

0.161

0.107

GPHP

0.589

0.464

0.527

3

SRYRQT

0.018

0.000

0.009

CPHP

0.018

0.000

0.009

4

SRYHQT

0.018

0.036

0.027

GLHP

0.018

0.000

0.009

5

SRYQLT

0.018

0.018

0.018

GPRP

0.143

0.161

0.152

6

GCYQQT

0.036

0.018

0.027

    

7

GRPQQT

0.018

0.018

0.018

    

8

GRYQQI

0.000

0.018

0.009

    

9

GRYRQT

0.161

0.036

0.098

    

10

GRYHQT

0.000

0.018

0.009

    

11

GRYNQT

0.000

0.018

0.009

    

12

GRYKQT

0.071

0.036

0.054

    

13

GRYQLT

0.143

0.089

0.116

    
 

Genotypic frequencies

       
  

n/28

n/28

n/56

n/28

n/28

n/56

 

1

GRYQQT/GRYQQT

0.357

0.464

0.411

GPHS/GPHS

0.107

0.286

0.196

2

SRYQQT/SRYQQT

0.00

0.107

0.054

GPHS/GPHP

0.250

0.179

0.214

3

SRYQQT/SRYRQT

0.036

0.00

0.018

GPHP/GPHP

0.286

0.214

0.250

4

SRYQQT/SRYHQT

0.036

0.071

0.054

CPHP/GPHP

0.036

0.00

0.018

5

SRYQQT/SRYQLT

0.036

0.036

0.036

GLHP/GPHP

0.036

0.00

0.018

6

GRYQQT/GCYQQ

0.071

0.036

0.054

GPRP/GPHP

0.286

0.32

0.304

7

GRPQQT/GRYKQ

0.036

0.036

0.036

    

8

GRYQQT/GRYQQI

0.00

0.036

0.018

    

9

GRYQQT/GRYRQT

0.107

0.036

0.071

    

10

GRYRQT/GRYRQT

0.071

0.000

0.036

    

11

GRYRQT/GRYQLT

0.071

0.036

0.054

    

12

GRYHQT/GRYNQT

0.000

0.036

0.018

    

13

GRYKQT/GRYQLT

0.071

0.00

0.036

    

14

GRYQQT/GRYKQT

0.036

0.036

0.036

    

15

GRYQLT/GRYQLT

0.071

0.071

0.071

    
  1. Alleles and genotypes associated with susceptibility/resistance to scrapie are underlined.