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Table 1 Combinations of wild-type (WT) and aberrantly spliced introns used in SFV DNA/RNA layered vectors.

From: Novel viral vectors utilizing intron splice-switching to activate genome rescue, expression and replication in targeted cells

Luc gene

Intron in nsP4

Luc0

LucWT

Luc7

Luc6+7

None

nc

A1

A2

A3

WT

B0

B1

Nc

nc

C654T

C0

nc

C2

nc

T705G

D0

nc

D2

nc

C654C + T705G

E0

nc

Nc

E3

  1. nc: vector not constructed.
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Virology Journal

ISSN: 1743-422X