Skip to main content
Figure 6 | Virology Journal

Figure 6

From: Novel viral vectors utilizing intron splice-switching to activate genome rescue, expression and replication in targeted cells

Figure 6

Rescue of the activity of the SFV DNA/RNA layered replication-competent vectors by SSOs. HeLa cells were mock transfected (control cells, indicated as "none") or transfected with SSOs (ON654, ON705 or their combination) at a final concentration 100 nM 24 hours prior to transfection with vectors B1, C2, D2 or E3. Infectivity of constructs was indirectly estimated by measuring the luciferase activity at 16 h post-transfection; luciferase activities, normalized to that in cells transfected with B1 vector in the absence of SSOs (100%), are represented on the vertical axis. Error bars represent standard deviations; the results of one of three reproducible experiments are shown

Back to article page