Antibody response in mice. Group of BALB/c mice were immunized with the MEAP, inactivated Sav vaccine and PBS. Serum samples (10 mice per group) were collected at various time points, and endpoint antibody titers against HSV-2 were determined by EIA. All the measurements were made in triplicate, with the mean ± standard error (SE) shown. P < 0.05 compared with groups immunized with PBS or inactivated vaccine.