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Table 4 The CC50 and CC90 values of BmPCP in different cells a

From: Inhibitory activity of 9-phenylcyclohepta[d]pyrimidinedione derivatives against different strains of HIV-1 as non-nucleoside reverse transcriptase inhibitors

Cells CC50b (μM) CC90 (μM) b
TZM-bl 90.26 ± 2.73 207.93 ± 8.69
PBMC 114.5 ± 9.38 228.56 ± 6.40
MT4 165.29 ± 30.40 382.59 ± 53.52
  1. aThe compound was tested in triplicate and the data are presented as means ± SD.
  2. bXTT assay was used to determine the 50% or 90% cytotoxic concentration (CC50 or CC90)