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Table 2 Comparison of important characteristics between 166 patients with the wild type A336/T337 and A336C/A336T/T337C variants

From: A336C/A336T/T337C variations in HBV core gene and spontaneous hepatitis B e antigen loss in chronic hepatitis B patients

 

A336/T337

(n = 126)

C336/T336/C337

(n = 40)

χ2

p value

HBeAg

  

12.1

0.001

Positive

68

9

  

Negative

58

31

  

G1896 variation

  

4.7

0.03

G1896

75

16

  

A1896

51

24

  

HBV genotype

  

3.4

0.07

B

61

26

  

C

65

14

  

serum HBV DNA levels

    

<6

69

31

6.6

0.01

≥6

57

9

  

Age

    

<35

62

18

0.2

0.64

≥35

64

22

  

Sex

  

2.4

0.12

Male

100

27

  

Female

26

13

  

Serum ALT levels

  

0.1

0.74

≤50 U/L

75

25

  

>50 U/L

51

15