Table 1 Basic characteristic of patients with severe H1N1and moderate H1N1
Variable | severe H1N1 (n= 36) | moderate H1N1 (n= 40) | P-value |
|---|---|---|---|
Age, mean ± SD, years* | 40.1 ±18.6 | 26.1 ± 8.0 | 0.006 |
Male/Female distribution, N (%) ▲ | 20/25(55%/45%) | 20/20(50%/50%) | 0.653 |
Prodromal symptoms, N (%) ▲ | |||
Fever(T > 38.5) | 28(78) | 16(40) | 0.001 |
Cough | 26(72) | 28(70) | 1.000 |
Dyspnea | 13(36) | 0 | <0.001 |
Gastrointestinal | 4(11) | 3(7) | 0.702 |
Myalgia | 23(64) | 10(25) | 0.001 |
Co-morbidities, N (%) ▲ | |||
COPD | 12(33) | 0 | <0.001 |
Coronary artery disease | 4(11) | 0 | <0.001 |
Diabetes mellitus | 5(14) | 2(5) | 0.246 |
Hypertension | 5(14) | 2(5) | 0.246 |
Pregnancy | 4(11) | 1(2.5) | 0.131 |
Others (Hypothyroidism, Immunosuppression, Transplant) | 3(8) | 0 | 0.102 |
Changes in lung imaging examination, N (%) ▲ | 20(55) | 3(7) | <0.001 |
Patients using Oseltamivir, N (%) ▲ | 36(100) | 40(100) | 1.000 |
Oseltamivir treatment time, mean ± SD, (days)* | 8.55 ± 3.39 | 3.60 ± 1.00 | <0.001 |
Patients using combined glucocorticoid, N (%) ▲ | 19(53) | 0 | <0.001 |
The number of people using the ventilato, N (%) ▲ | 5(14) | 0 | <0.001 |
Average stay, mean ± SD, days* | 13.71 ± 4.77 | 3.37 ± 1.06 | <0.001 |
Death toll, N (%) ▲ | 1(3) | 0 | 0.474 |