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Figure 3 | Virology Journal

Figure 3

From: Serine 204 phosphorylation and O-β-GlcNAC interplay of IGFBP-6 as therapeutic indicator to regulate IGF-II functions in viral mediated hepatocellular carcinoma

Figure 3

A homology model of human IGFBP-6 utilizing automated protein modeling option was retrieved through I-TASSER server. Five models were received from the server utilizing five different templates namely: model 1-5 through this option. Among the five, one that covered all amino acids with alpha helix structure and beta pleated sheet, high resemblance with experimentally determined C-terminal and high C-value was selected. This model shows that predicted Yin Yang sites have high surface accessibility for the phosphorylation and O-β-GlcNAc interplay. The Ser and Thr residues are denoted by red and green colors respectively.

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