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Table 3 Interacting enzymes predicted by Scansite.

From: Positional effect of phosphorylation sites 266 and 267 in the cytoplasmic domain of the E2 protein of hepatitis C virus 3a genotype: Interferon Resistance analysis via Sequence Alignment

Sitea

Enzymeb

Gene Card

UniGenec

UniProtc

Full Name

S66

PKC alpha/beta/gamma

PRKCA

Yes

P17252

Protein kinase C, alpha

 

Casein Kinase 1

CSNK1G2

Yes

P78368

casein kinase 1, Gamma 2

Y226

Src Kinase

SRC

Yes

P12931

V-Src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

 

Protein Kinase A

PRKACG

Yes

P22612

Protein kinase, cAMP-dependent, catalytic, gamma

S267

PKC alpha/beta/gamma

PRKCA

Yes

P17252

Protein kinase C, alpha

 

Akt Kinase

AKT1

Yes

P31749

v-akt murine thymoma viral oncogene homolog 1

  1. a) Phosphorylation sites in the envelope gene.
  2. b) Observed enzymes by the Scansite.
  3. c) Gene's availability on UniGene and UniProt.
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Virology Journal

ISSN: 1743-422X