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Table 2 Summary of predicted tyrosine phosphorylation sites.

From: Positional effect of phosphorylation sites 266 and 267 in the cytoplasmic domain of the E2 protein of hepatitis C virus 3a genotype: Interferon Resistance analysis via Sequence Alignment

Sitea aab Contextc NetPhos d Scansite e NetSurfPf I-TASSERg
66 *S* ATTASVRSH 0.869   E Yes
266 *S* PRRLSSCKP 0.978 Y E Yes
267 *S* RRLSSCKPI 0.983 Y E Yes
356 *S* LRPPSGRWF 0.992   E No
311 *T* VKAATVCGP 0.512   E No
  1. a) Phosphorylation sites in the local 3a sequences of the envelope genes.
  2. b) S indicates Serine; T is for Threonine and Y for Tyrosine predictions.
  3. c) Region where the phosphorylation sites are available.
  4. d) Predicted sites by NetPhos with a score of ≥ 0.8. Dashes indicate lack of Phosphorylation sites in that position.
  5. e) Y indicates predicted sites in sequence on "Low Stringency". Dashes indicate lack of Phosphorylation sites in that position.
  6. f) E indicates Exposed sites and B indicates Buried sites. Surface accessibility calculated by NetSurfP.
  7. g) Ab-initio 3D model was constructed by using I-TASSER server.