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Table 3 Sequence similarities and characterization of differentially expressed transcripts of Chicken Embryo Lung Cells (CeLu)

From: Cellular transcripts regulated during infections with Highly Pathogenic H5N1 Avian Influenza virus in 3 host systems

Clone Name

Identity

Accession Number

Homology (%)

Putative functional role

DEG 1

PREDICTED: Gallus gallus similar to Prenyl (decaprenyl) diphosphate synthase, subunit 2 (LOC421777), mRNA (down regulated)

XM419804

96%

Catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.

DEG 2

Dendrobium crumenatum class-1 small heat shock protein mRNA, partial cds (up regulated)

EU302124

100%

Elevated temperatures or stress induced proteins, in which its expression is transcriptionally controlled.

DEG 3

Clonorchis sinensis clone CMXR-GP4 unknown mRNA (up regulated)

EU309047

100%

 

DEG 4

Influenza A virus (A/open-billed Stork/Nakhonsawan/BBA0627May/05(H5N1)) polymerase PA (PA) gene, complete cds (up regulated)

EF112270

99%

Subunit of the trimeric complex of the RNA-dependent-RNA polymerase of Influenza A, involved in transcription of viral RNAs

DEG 5

Clonorchis sinensis clone ACP-1U-117-2 (down regulated)

EU780119

100%

 

DEG 6

Tigriopus japonicus mitochondrial heat shock protein 60 (Hsp60) mRNA, complete cds; nuclear gene for mitochondrial product (up regulated)

EU306562

99%

Mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. Involved in stress response from cells, especially during infection.

DEG 7

PREDICTED: Gallus gallus hypothetical LOC418666 (LOC418666), mRNA (up regulated)

XM416862

94%

 

DEG 8

PREDICTED: Gallus gallus hypothetical LOC426258 (LOC426258), mRNA (down regulated)

XM423923

100%

 

DEG 9

Unknown sequence (down regulated)

   

DEG 10

Unknown sequence (down regulated)

   

DEG 11

Sus scrofa calcium transporter 1 (TRPV6) mRNA, partial cds (down regulated)

FJ268731

100%

Membrane calcium channel which regulates calcium entry into the cell and also plays a role in calcium reabsorption.