Table 3 Sites under differential selection between isolates from seasonal human and the pandemic 2009 clusters
From: Positive selection on hemagglutinin and neuraminidase genes of H1N1 influenza viruses
| Protein | Position1 | P-value | Amino acid polymorphism2 | |
|---|---|---|---|---|
| Pandemic 2009 strains | Seasonal human strains | |||
| HA | 34BT | 0.00286 | E1886/G2/X2/K1 | E1404 |
| 39 | 0.00054 | G1887/E3/R1 | G1404 | |
| 86B | 0.00233 | D1856/G31/N2/Y1/E1 | E1383/K19/G1/Q1 | |
| 94B | 0.00014 | D1885/N4/E1/X1 | Y769/H574/D38/N19/Q2/A1/R1 | |
| 153BT | 0.00786 | K1891 | G1132/E202/R28/K20/X18/V4 | |
| 160BG | 0.00073 | K1890/E1 | N1345/K27/X12/S7/T7/D2/E2/A1/I1 | |
| 187BR | 0.00445 | D1884/G5/X2 | D1072/X135/N132/V30/E23/G9/A2/I1 | |
| 197 | 0.00073 | A1851/T23/S17 | A1401/T3 | |
| 202B | 0.00318 | G1886/X4/W1 | V1378/L17/A5/M4 | |
| 203 | 0.00828 | T1341/S542/X7/A1 | S1392/T10/F1/X1 | |
| 224B | 0.00973 | E1885/Q1/X5 | E1342/A45/H5/P5/K4/T2/S1 | |
| 234 | 0.00628 | V1883/I7/L1 | L1404 | |
| 237B | 0.00445 | G1890/X1 | G1379/R19/E6 | |
| 250T | 0.00002 | V1884/I4/A2/L1 | A1404 | |
| 282 | 0.00653 | P1872/L10/S7/T1/X1 | P1404 | |
| 302B | 0.00098 | K1880/E8/N1/T1/R1 | E1403/G1 | |
| 339 | 0.00174 | G1888/R2/E1 | G1404 | |
| 374 | 0.00550 | E1608/K275/G8 | G1398/R4 | |
| 391 | 0.00564 | T1888/A2/I1 | T1404 | |
| 399 | 0.00303 | H1890/X1 | K1383/N16/R3/E1/T1 | |
| 430T | 0.00605 | E1889/D1/K1 | E1404 | |
| 473T | 0.00803 | N1890/D1 | D1001/N403 | |
| 527T | 0.00513 | V1873/I12/A2/L2/X2 | L1403/V1 | |
| 541T | 0.00052 | G1866/W12/H6/M3/Y1/-3 | G1404 | |
| NA | 2 | 0.00001 | N1313/-79/I2/S1/X1 | N1532/-200/K3 |
| 6 | 0.00009 | K1350/-42/N3/R3 | K1634/R14/-87 | |
| 35 | 0.00151 | S1392/G2/C1/I1/V1 | S1733/N1/G1 | |
| 52TG | 0.00510 | S1397 | R1686/K17/S17/N9/G4/X1/-1 | |
| 254 | 0.00188 | K1396/X1 | K1581/R154 | |
| 257 | 0.00119 | R1388/K8/X1 | K1735 | |