Table 3 Sites under differential selection between isolates from seasonal human and the pandemic 2009 clusters

HA

34^BT

0.00286

E1886/G2/X2/K1

E1404

39

0.00054

G1887/E3/R1

G1404

86^B

0.00233

D1856/G31/N2/Y1/E1

E1383/K19/G1/Q1

94^B

0.00014

D1885/N4/E1/X1

Y769/H574/D38/N19/Q2/A1/R1

153^BT

0.00786

K1891

G1132/E202/R28/K20/X18/V4

160^BG

0.00073

K1890/E1

N1345/K27/X12/S7/T7/D2/E2/A1/I1

187^BR

0.00445

D1884/G5/X2

D1072/X135/N132/V30/E23/G9/A2/I1

197

0.00073

A1851/T23/S17

A1401/T3

202^B

0.00318

G1886/X4/W1

V1378/L17/A5/M4

203

0.00828

T1341/S542/X7/A1

S1392/T10/F1/X1

224^B

0.00973

E1885/Q1/X5

E1342/A45/H5/P5/K4/T2/S1

234

0.00628

V1883/I7/L1

L1404

237^B

0.00445

G1890/X1

G1379/R19/E6

250^T

0.00002

V1884/I4/A2/L1

A1404

282

0.00653

P1872/L10/S7/T1/X1

P1404

302^B

0.00098

K1880/E8/N1/T1/R1

E1403/G1

339

0.00174

G1888/R2/E1

G1404

374

0.00550

E1608/K275/G8

G1398/R4

391

0.00564

T1888/A2/I1

T1404

399

0.00303

H1890/X1

K1383/N16/R3/E1/T1

430^T

0.00605

E1889/D1/K1

E1404

473^T

0.00803

N1890/D1

D1001/N403

527^T

0.00513

V1873/I12/A2/L2/X2

L1403/V1

541^T

0.00052

G1866/W12/H6/M3/Y1/-3

G1404

NA

2

0.00001

N1313/-79/I2/S1/X1

N1532/-200/K3

6

0.00009

K1350/-42/N3/R3

K1634/R14/-87

35

0.00151

S1392/G2/C1/I1/V1

S1733/N1/G1

52^TG

0.00510

S1397

R1686/K17/S17/N9/G4/X1/-1

254

0.00188

K1396/X1

K1581/R154

257

0.00119

R1388/K8/X1

K1735