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Table 1 Positively selected sites in hemagglutinin from viruses from different clusters

From: Positive selection on hemagglutinin and neuraminidase genes of H1N1 influenza viruses

Dataset

Description

Number of sequences

Length of alignment (bp)

Number of sites under positive selection

Positively selected sites1

      

HA1

HA2

    

SLAC

FEL

SLAC

FEL

SLAC

FEL

1.1

Avian strains

75

1647

0

0

    

1.2

North American swine strains

196

1647

0

1

 

138

  

1.3

Eurasian swine strains

90

1647

0

1

   

399

1.4

Seasonal human strains

1404

1647

8

8

82B,94B, 141B,162BG,186B,187BR,222BR

82B,94B,160BG,162BG,186B,187BR,222BR

451T

451T

1.5

Pandemic 2009 human strains

1891

1647

7

9

186B,197,203,205B,222BR,223B,261BT

186B,197,203,222BR,261BT

 

411T,451T,460T,530T

  1. 1In these columns, B indicates that the site lies in the B-cell antigenic regions [18]. G means that it is a potential glycosylation site. T indicates that the site lies in the T-cell antigenic regions [19]. R indicates that it is a receptor-binding site [11]. We use the same numbering strategy as Deem and Pan [18] and start numbering from the amino acids DTLC.