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Figure 6 | Virology Journal

Figure 6

From: The NS1 protein of influenza a virus interacts with heat shock protein Hsp90 in human alveolar basal epithelial cells: Implication for virus-induced apoptosis

Figure 6

A proposed model for the molecular mechanism of NS1-induced apoptosis. Binding of NS1 protein to Hsp90 might compete off the Apaf-1, resulting in the oligomerization of Apaf-1 which promotes the interaction between Apaf-1 and Cyt c and lead to the activation of caspase 9 and caspase 3 and thus the cell apoptosis occur.

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Virology Journal

ISSN: 1743-422X