Table 1 The amino acid substitutions in the persistent virus*
From: Establishment of persistent infection with foot-and-mouth disease virus in BHK-21 cells
Viral protein | Mutation types and positions |
|---|---|
2C | Glu→ Ala (aa 1174) |
2C | Val→ Leu (aa 1389) |
2C | Pro→ Thr (aa 1394) |
2C | Asn→ Ser (aa 1418) |
3A | Ile→ Val (aa 1498) |
3A | Thr→ Asn (aa 1522) |
3A | Lys→ Val (aa 1535) |
3A | Asp→ Asn (aa 1563) |
3B1 | Leu→ Arg (aa 1584) |
3B3 | Lys→ Asn (aa 1642) |
3C | Glu→ Gln (aa 1698) |
3C | Asp→ Asn (aa 1753) |
3C | Gly→ Arg (aa 1779) |
3D | Glu→ Lys (aa 2009) |
3D | Val→ Leu (aa 2187) |