Schematic representation of GCRV NS80 conserved regions and potential functional domains. (A) NS80 conserved regions and potential functional domains. '+ (-) VFLS' indicated formation (not formation) of viral factory-like structures. (B) Multiple sequence alignment of NS80 and its homologues. Conserved residues were highlighted in black. 'X4 or X12 (painted in gray)' respectively showed four or twelve amino acid residues without any similarities.