Relative survival of infected cells as determined by WST-1 assay. Cytopathic activity of RL-07 (grey bar) compared to wtHAdV-5 (black bar) is higher on primary high grade glioma cell cultures. Error bars represent SD (n = 4). * - statistical significance; paired, two sided t-test, p < 0.01. Cells were seeded in 96-well plates 1 day prior infection with RL-07 and wtHAdV-5 (MOI range 0-100 pfu/cell). Viability of the cultures was determined by WST-1 assay 7 days p.i..