Enhanced expression of PGE2 and cell proliferation in Core transfected Huh-7 cells. (A) Prostaglandin E2 production in response to HCV 1a and 3a Core transfected Huh-7 cells were measured with Biotrak Prostaglandin E2 Enzyme Immunoassay system. (B) MTT assay shows that HCV 3a Core significantly increased the proliferation of Huh-7 cells as compared to mock and Core 1a transfected cells, observed at 570 nm wavelength. All experiments were performed in 3 independent experiments having triplicate samples in each. Error bars indicate, mean S.D, *p < 0.01 verses mock.