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Table 4 Comparison of demographic, biochemical parameters as well as Complications and mortality frequencies among patients infected with genotype 4 HEV with and without liver cirrhosis

From: Clinical characteristics and risk factors of sporadic Hepatitis E in central China

Parameter HEV P value
Number of patients 40 170 -
Age in years 51.78 ± 14.70 48.02 ± 14.55 NS
Gender(male/female) 36/4 143/27 NS
Mortality 10(25%) 11(6.47%) 0.002
Complications    
Spontaneous peritonitis 24(60%) 14(8.24%) < 0.001
Upper gastrointestinal hemorrhage 2(5%) 4(2.35%) NS
Hepatorenal syndrome 8(20%) 5(2.94%) < 0.001
Hepatic encephalopathy 6(15%) 8(4.71%) 0.03
ALT(U/L) 574.5(150.25-1612.25) 1158(478.75-1816.75) 0.02
AST(U/L) 310.5(117-1198.5) 670.5(208-1265.2) NS
GGT(U/L) 85(52.5-114.75) 131(67-229) 0.002
TBil(umol/L) 242.6(115.6-530.3) 197.93(82.6-298.85) NS
ALB(g/L) 31(27.65-32.98) 34.1(31.58-37.8) < 0.001
Tchol(mmol/L) 2.17(1.71-3.27) 3.18(2.45-3.9) < 0.001
CHE(U/L) 3014.5(2125.75-3967) 4356(3039.25-5752.25) 0.001
BUN (mmol/L) 5.5(4-9.29) 4.65(3.64-6) 0.032
Cr(umol/L) 64.9(55.35-116.6) 65.5(56.2-78.8) NS
PTA(%) 63(42-85) 93(72.95-113.5) < 0.001
INR 1.41(1.19-1.75) 1.13(1.04-1.29) < 0.001
  1. HEV, hepatitisE virus; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyltransferase; TBil, total bilirubin; ALB, albumin; ALP, alkaline phosphatase; Tchol, total cholesterol; LDH, lactate dehydrogenase; CHE, cholinesterase; BUN, blood urea nitrogen; Cr, creatinine; PTA, prothrombin activity; INR, international normalized ratio; and NS, not significant