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Table 3 Amino acid variations of the positively selected codons identified by M8

From: Positive selection in the hemagglutinin-neuraminidase gene of Newcastle disease virus and its effect on vaccine efficacy

Codon

Residue

Substitution frequencya

Hydrophobicityb

Charge

site ω( ± S.E.)c

266

A

91

Y

Neutral

1. 477 ± 0. 125

 

T

23

N

Neutral

 
 

V

10

Y

Neutral

 
 

I

4

Y

Neutral

 
 

P

2

Y

Neutral

 
 

D

1

N

Negative

 
 

S

1

N

Neutral

 

347

E

62

N

Negative

1. 485 ± 0. 100

 

G

41

Y

Neutral

 
 

K

28

N

Positive

 
 

N

1

N

Neutral

 

540

A

94

Y

Neutral

1. 438 ± 0. 202

 

V

23

Y

Neutral

 
 

T

15

N

Neutral

 
  1. a Numbers represent the occurrence times of each specific residue among the 132 HN sequences.
  2. b Y stands for hydrophobic and N for hydrophilic.
  3. c Estimated ω value at single site with standard error.