Analysis of codon usage and nucleotide composition bias in polioviruses

Table 5 Relative abundance of the 16 dinucleotides in ORF of 48 polioviruses

Dinucleotides	Range ^a	Mean ± S.D ^b	DVPV 1	Wild viruses	Vaccine
ApA	0.909-0.965	0.935 ± 0.016	0.943	0.955	0.937
ApG	0.993-1.083	1.048 ± 0.019	1.058	1.073	1.060
ApT	0.955-1.041	0.989 ± 0.019	0.999	1.018	0.999
ApC	0.960-1.040	1.007 ± 0.016	1.013	1.030	1.010
GpA	0.987-1.094	1.035 ± 0.020	1.043	1.071	1.038
GpG	1.140-1.266	1.215 ± 0.024	1.228	1.249	1.221
GpT	0.986-1.079	1.023 ± 0.021	1.033	1.057	1.028
GpC	0.846-0.950	0.895 ± 0.028	1.228	1.249	1.221
CpA	1.204-1.308	1.253 ± 0.032	1.270	1.293	1.268
CpG	0.418-0.538	0.490 ± 0.012	0.499	0.522	0.496
CpT	0.920-1.039	0.979 ± 0.033	0.995	1.022	0.997
CpC	0.952-1.035	0.991 ± 0.012	0.999	1.021	0.995
TpA	0.669-0.801	0.748 ± 0.034	0.766	0.787	0.766
TpG	1.386-1.474	1.423 ± 0.023	1.434	1.457	1.427
TpT	1.059-1.164	1.106 ± 0.029	1.122	1.144	1.118
TpC	0.824-0.973	0.914 ± 0.026	0.925	0.953	0.916

Note: The boldface means that the dinucleotide was over-represented or under-represented.
^a The range of coding region of 48 polioviruses's relative dinucleotide ratios
^b Mean values of coding region of 48 polioviruses's relative dinucleotide ratios ± S.D

ISSN: 1743-422X