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Figure 1 | Virology Journal

Figure 1

From: Effect of compounds on the purification and antibody preparation of the extracellular domain fragment of the receptor CD163

Figure 1

CD163 deletion constructs were used to prepare a polyclonal antibody of the fragment of the extracellular domain. (a) The structural domain organization of CD163 consists of 9 extracellular scavenger receptor cysteine-rich (SRCR) domains, 2 proline-serine-threonine (PST)-rich domains, a transmembrane region (TM domain), and a cytoplasmic tail. (b) The domain organization of the CD163 deletion mutants: For the tD4 mutant, the first 4 SRCR domains, the TM domain, and the cytoplasmic domain were deleted from wild type CD163. For the tD5 mutant, the first 5 SRCR domains, the TM domain, and the cytoplasmic domain were deleted from wild type CD163.

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Virology Journal

ISSN: 1743-422X