Skip to main content
Figure 3 | Virology Journal

Figure 3

From: Mutation of putative N-Linked Glycosylation Sites in Japanese encephalitis Virus Premembrane and Envelope proteins enhances humoral immunity in BALB/C mice after DNA vaccination

Figure 3

Analysis of JEV-induced IgG isotypes. Prime-boost-boost vaccinations were carried out. On day 7 (prime), day 21 (first boost) and day 35 (second boost) sera were taken and immunoglobulin isotypes were analyzed by ELISA. (A) IgG isotype response; (B) IgG1 isotype response; (C) IgG2a isotype response. Data presented as mean ± standard error for fourteen mice per group. ƟP < 0.05 compared with groups immunized with prME-WT in prime-boost-boost vaccinations.

Back to article page