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Table 7 TAHV is antigenically distinct from LACV and JCV by cross neutralizing antibody assay

From: Tahyna virus genetics, infectivity, and immunogenicity in mice and monkeys

Immunizing virusa

 

Serum neutralizing antibody titer against indicated virusb

 

Monkey #

LACV/78/NC-cl

JCV/61/CO-cl

TAHV/58/CZ-cl

LACV/78/NC-cl

DB70

2077

<10

383

 

DB8N

222

<10

<10

 

CK74

2782

<10

80

 

CL2G

326

<10

<10

 

DBCZ

4728

<10

169

 

CL6E

3719

<10

<10

 

DB0H

364

<10

<10

 

DA9F

1374

<10

82

 

GMTc:

1177

<10

36

JCV/61/CO-cl

A5E054

77

457

<10

 

A5E060

2825

352

282

 

A5E068

106

221

50

 

A5E069

85

712

168

 

A5E070

192

662

27

 

A5E073

140

256

49

 

A5E077

243

685

106

 

DBXG

107

407

163

 

GMT:

185

431

69

TAHV/58/CZ-cl

DBPN

92

14

1698

 

DBM6

58

<10

494

 

A5E006

15

<10

360

 

DBXJ

339

31

3195

 

A5E036

113

<10

316

 

L27

15

<10

215

 

DC11

151

<10

1613

 

GMT:

68

11

725

  1. a Monkeys were immunized subcutaneously with 5 log10 PFU of indicated virus and serum was collected on day 28.
  2. b Reciprocal PRNT60 assayed against indicated virus. Lower limit of detection is 10.
  3. b Geometric mean titer. For the purpose of calculation, a value of 9 was assigned to monkeys with titers less than 10.
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