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Table 4 Tahyna virus TAHV/58/CZ-cl(1) is immunogenic in rhesus monkeys in the absence of viremia

From: Tahyna virus genetics, infectivity, and immunogenicity in mice and monkeys

Monkey Number

Peak virus titera (log10PFU/mL)

Neutralizing antibody titer on indicated dayb

  

0

42

DBPN

<0.7

<10

2673

DBM6

<0.7

<10

1472

A5E006

<0.7

<10

244

DBXJ

0.7

<10

8379

A5E036

<0.7

<10

1284

L27

<0.7

<10

64

L22

<0.7

<10

<10d

DC11

<0.7

<10

701

 

GMTc:

< 10

896

  1. a Serum was collected on days 0, 2, 4, 6, 8, 10, 14, 21, 28, and 42. Viremia was detectable only on day 4 in one monkey. Lower limit of detection is 0.7 log10PFU/mL.
  2. b Reciprocal PRNT60 against TAHV/58/CZ-cl(1). Lower limit of detection is 10.
  3. c Geometric mean neutralizing antibody titer.
  4. d Monkey considered uninfected and PRNT not used in GMT calculation.
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Virology Journal

ISSN: 1743-422X