Tahyna virus genetics, infectivity, and immunogenicity in mice and monkeys

Table 3 Tahyna virus is highly infectious and neurovirulent for weanling Swiss Webster mice, but strains differ in neuroinvasiveness

^a Groups of weanling Swiss Webster mice (21-23 days old) were inoculated intraperitoneally with 100 μL of diluted virus (0 - 5 log₁₀ PFU).
^b Groups of weanling Swiss Webster mice (21-23 days old) were inoculated intracerebrally with 10 μL of diluted virus (1 - 4 log₁₀ PFU).
^c LD₅₀ = Lethal dose 50%.
^d ID₅₀ = Infectious dose 50%.
^e Neuroinvasive phenotype: Low = LD₅₀ ≥ 3.5 log₁₀ PFU; High = LD₅₀ ≤ 1.5 log₁₀ PFU. Neurovirulent phenotype: High = LD₅₀ < 1.5 log₁₀ PFU.

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