Figure 7From: Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulenceInterferon production in M1 cells. Monloayers of M1 cells were infected with the parental recombinant viruses rHK-wt, rPR8-wt and rWSN-wt and the different recombinant viruses, rPR8-HK-NS, rPR8-H5N1-NS and rWSN-Ck/Bj-NS viruses at MOI = 2. Twenty-four hours post infection, the supernatants were collected and the level of IFN-β production was assessed by ELISA. The IFN-β levels were compared to a positive control (VSV Δ51 infection). Values are shown as average +/- standard deviation.Back to article page