Figure 5
From: A gastrointestinal rotavirus infection mouse model for immune modulation studies
T-cell proliferation by antigen-specific stimulation with rotavirus RRV. Spleen cells of individual mice were isolated at day 28 and 1 × 106 cells were stimulated with 5 × 107 CCID50 UV-inactivated RRV for 5 days. Proliferation of T cells was determined by measuring incorporation of tritium-thymidine. Bars represents the stimulation index (RRV stimulated cells/non-stimulated cells) ± SEM per group. The RRV + EDIM group as well as the Gastrogard-R® group showed a significant increase in T cell proliferation (p < 0.05 and p < 0.0001 respectively) compared to non-infected mice (control).