Enhancement of anti-DIII antibodies by the C3d derivative P28 results in lower viral titers and augments protection in mice

Table 2 FRNT and Mouse Survival

Sample	Group	Survival [# pooled/# in vaccinated group]	FRNT50*	FRNT80	FRNT50	FRNT80
GG			Pre-infection		Post-infection
1	DIII	Yes [4/5]	640	80	2560	320
2	DIII	No [1/5]	<20	<20
3	DIII-P28	Yes [3/5]	320	80	1280	320
4	DIII-P28	No [2/5]	40	20
5	ectoE	Yes [4/5]	320	320	2560	640
6	ectoE	No [1/5]	40	<20
7	ectoE-28	Yes [5/5]	640	320	2560	640
8	prM/E	Yes [5/5]	320	160	1280	640
9	naïve	No [5/5]	20	<20
IM			Pre-infection		Post-infection
10	DIII	No [5/5]	<20	<20
11	DIII-p28	Yes [3/5]	20	<20	1280	640
12	DIII-p28	No [2/5]	20	<20
13	ectoE	Yes [4/5]	40	20	2560	1280
14	ectoE	No [1/5]	20	<20
15	ectoE-p28	Yes [3/5]	40	20	2560	640
16	ectoE-p28	No [2/5]	<20	<20
17	prM/E	Yes [5/5]	320	160	2560	640
18	vector	Yes [1/5]	40	<20	640	80
19	vector	No [4/5]	<20	<20

ISSN: 1743-422X