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Table 1 Anti-DIII Antibody Isotypes

From: Enhancement of anti-DIII antibodies by the C3d derivative P28 results in lower viral titers and augments protection in mice

C57BL/6

    

Gene Gun

IgG1

IgG2a*

IgG2b

IgG2c

DIII

0.44

N.A.

0.18

0.00

DIII-P28

0.43

N.A.

0.24

0.00

Ecto E

0.41

N.A.

0.19

0.00

Ecto E-P28

0.38

N.A.

0.12

0.01

prM/E

0.44

N.A.

0.36

0.18

C57BL/6

    

Intramuscular

IgG1

IgG2a

IgG2b

IgG2c

DIII

0.13

N.A.**

0.01

0.04

DIII-P28

0.41

N.A.

0.14

0.02

Ecto E

0.23

N.A.

0.08

0.00

Ecto E-P28

0.23

N.A.

0.04

0.01

prM/E

0.25

N.A.

0.20

0.11

  1. *IgG2a isotype not expressed in C57BL/6 mice.
  2. **N.A. = Not applicable since the IgG2a subtype is not expressed in C57BL/6 mice.
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Virology Journal

ISSN: 1743-422X