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Table 3 The co-existence of EBV BZLF1 gene promoter zone (Zp) variants and EBV subtypes in each EBV-related disease study group.

From: Characterization of variants in the promoter of BZLF1 gene of EBV in nonmalignant EBV-associated diseases in Chinese children

Co-infection

%(n/N)

IM

(n = 88)

HLH

(n = 46)

CAEBV

(n = 32)

Controls

(n = 40)

Zp-P+V1

6.8 (6/88)

0

0

2.5(1/40)

Zp-P+V4

5.7 (5/88)

4.3 (2/46)

0

5.0 (2/40)

Zp-P+V3

2.3 (2/88)

26.1(12/46)

37.5(12/32)

0

Total

14.8 (13/88)

30.4(14/46)

37.5(12/32)

7.5 (3/40)

  1. * Four patients detected in CAEBV with both type 1 and type 2 co-infections were also presented with Zp-P and Zp-V3 co-exsistences.